Regulating Hypothalamus Gene Expression in Food Intake: Dietary Composition or Calorie Density?

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Regulating Hypothalamus Gene Expression in Food Intake: Dietary Composition or Calorie Density?

BACKGROUND The proportion of saturated fatty acids/unsaturated fatty acids in the diet seems to act as a physiological regulation on obesity, cardiovascular diseases, and diabetes. Differently composed fatty acid diets may induce satiety of the hypothalamus in different ways. However, the direct effect of the different fatty acid diets on satiety in the hypothalamus is not clear. METHODS Thre...

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Letter: Regulating Hypothalamus Gene Expression in Food Intake: Dietary Composition or Calorie Density? (Diabetes Metab J 2017;41:121-7)

Corresponding author: Bo Kyung Koo https://orcid.org/0000-0002-6489-2656 Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul National University College of Medicine, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul 07061, Korea E-mail: [email protected] Jang et al. [1] reported that high saturated fatty acid (SFA) or n-3 polyunsatura...

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Response: Regulating Hypothalamus Gene Expression in Food Intake: Dietary Composition or Calorie Density? (Diabetes Metab J 2017;41:121-7)

Corresponding author: Jong-Yeon Kim https://orcid.org/0000-0002-1481-7615 Obesity-Diabetes Advanced Research Center, Yeungnam University College of Medicine, 170 Hyeonchung-ro, Nam-gu, Daegu 42415, Korea E-mail: [email protected] We appreciate Dr. Koo’s interest and comments on our article entitled “Regulating hypothalamus gene expression in food intake: dietary composition or calorie density?” w...

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Metformin inhibits food intake and neuropeptide Y gene expression in the hypothalamus

Metformin may reduce food intake and body weight, but the anorexigenic effects of metformin are still poorly understood. In this study, Sprague-Dawley rats were administered a single intracere-broventricular dose of metformin and compound C, in a broader attempt to investigate the regula-tory effects of metformin on food intake and to explore the possible mechanism. Results showed that central ...

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Regulating food intake.

EVERY ORGANISM INGESTS FOOD (energy). If it takes in too little, it will starve; if it takes in too much, it will become obese. Too little is readily defined as caloric intake less than expenditure, and too much is simply the opposite. Multiple regulatory pathways are known that promote and inhibit feeding and thus regulate energy balance. However, these pathways and their interactions remain i...

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ژورنال

عنوان ژورنال: Diabetes & Metabolism Journal

سال: 2017

ISSN: 2233-6079,2233-6087

DOI: 10.4093/dmj.2017.41.2.121